TWO SEPARATION-OF-FUNCTION ISOFORMS OF HUMAN TPP1 DICTATE TELOMERASE REGULATION IN SOMATIC AND GERM CELLS



Achieving Effective and Efficient Basal Insulin Optimal Management by Using Mobile Health Application (APP) for Type 2 Diabetes Patients in China

Xiaoling Cai,1 Fang Zhang,1 Chu Lin,1 Xiaomei Zhang,2 Zhufeng Wang,3 Huifang Xing,4 Lin Nie,5 Xueyao Han,1 Linong Ji1 1Department of Endocrinology and Metabolism, Peking University People’s Hospital, Beijing, People’s Republic of China; 2Department of Endocrinology and Metabolism, Peking University International Hospital, Beijing, Peopl

read more

Engineering PTEN-L for Cell-Mediated Delivery

The tumor suppressor Display Cabinet PTEN is frequently inactivated in glioblastoma.PTEN-L is a long form of PTEN produced by translation from an alternate upstream start codon.Unlike PTEN, PTEN-L has a signal sequence and a tract of six arginine residues that allow PTEN-L to be secreted from cells and be taken up by neighboring cells.This suggests

read more